A Study Of The Effect Of Sandarac Resin (Tetraclinis Articulate) Extract On Wound Treatment
Keywords:
Biological Activity, Wound Treatment, Resin Extract, SandaracAbstract
The main objective of the research is to obtain sandarac resin (Tetraclinis articulate) using traditional techniques (soaking method), and to assess the extract's impact as a bio-inhibitor for some types of bacteria and to know the effective groups such as (Tannins, phenols, resins, flavonoids, saponins, alkaloids and terpenes). The biological activity of the extract against bacterial and fungi species was measured. The results of the antimicrobial activity detection test shows that the effect of the extract at concentrations (50%, 25%) on Staphylococcus aureus ATCC (6538) inhibited activity (15 mm, 14 mm), respectively, and showed the antibiotic (Gentamycin) 17 mm inhibitory activity. The extract showed at concentrations (50%, 25%) activity against Staphylococcus epidermidis (local isolate) inhibitory activity (16 mm, 15 mm), while the inhibitory activity of the antibiotic (Gentamycin) was (17 mm) and the effectiveness of the extract (50%, 25%) has inhibitory activity on Streptococcus mutans (local isolate) (14 mm, 12 mm) and the antibiotic activity (17 mm). The extract (50%, 25%) showed inhibitory activity (15). mm, 14 mm) on E. coli ATCC (105538), respectively while the antibiotic had inhibitory activity (17 mm). The extract (at concentrations of 50%, 25%) showed a higher inhibitory activity on Candida albicans ATCC (10231) where the inhibitory activity was (13 mm, 12 mm), while Nystatin showed inhibitory activity (16 mm).
Downloads
References
Singh N, Yadav SS, Kumar S, Narashiman B. A review on traditional uses, phytochemistry, pharmacology, and clinical research of dietary spice Cuminum cyminum L. Phytother Res. 2021 Sep;35(9):5007-5030
Singh N, Yadav SS, Kumar S, Narashiman B. A review on traditional uses, phytochemistry, pharmacology, and clinical research of dietary spice Cuminum cyminum L. Phytother Res. 2021; 35(9):5007-5030
Al-Snafi EA , The pharmacological activities of Cuminum cyminum - A review , IOSR Journal of Pharmacy, 2016; 6 (6):46-65.
El Hartiti H, El Mostaphi A, Barrahi M, Aouatif B, Chahboun N, Amiyare R, Zarrouk, A et al. Chemical composition and antibacterial activity of the essential oil of Myrtus communis leaves, Karbala International Journal of Modern Science, 2020; 6 (3), Article 3.
Alebachew T, Yismaw G, Derabe A, Sisay Z. Staphylococcus aureus burn wound infection among patients attending yekatit 12 hospital burn unit, addis ababa, Ethiopia. Ethiop J Health Sci. 2012;22(3):209-13.
Alizadeh Behbahani B, Noshad M, Falah F. Cumin essential oil: Phytochemical analysis, antimicrobial activity and investigation of its mechanism of action through scanning electron microscopy. Microb Pathog. 2019; 136:103716.
George M. Qualitative & Quantitative Phytochemical analysis on the Leaves &fruits of Passiflora foetida. International Journal of Pharmaceutical Science Invention, 2017; 6 (3): 26-30
Singh N, Yadav SS, Kumar S, Narashiman B. A review on traditional uses, phytochemistry, pharmacology, and clinical research of dietary spice Cuminum cyminum L. Phytother Res. 2021 ;35(9):5007-5030.
Khan IU, Mehriya ML, Rathore BS, Kumhar SR and Singh B. Evaluation of volatile phytochemical constituents in cumin (Cuminum cyminum) genotypes by gas chromatography-mass spectroscopy, journal of Pharmacognosy and Phytochemistry, 2017; 6(3).
Mostafa AA, Al-Askar AA, Almaary KS, Dawoud TM, Sholkamy EN, Bakri MM. Antimicrobial activity of some plant extracts against bacterial strains causing food poisoning diseases. Saudi J Biol Sci. 2018;25(2):361-366.
Sen, A.K., Sen, D.B., Maheshwari, R.A. Extraction, Isolation, and Quantitative Determination of Flavonoids by HPLC. In: Sen, S., Chakraborty, R. (eds) Herbal Medicine in India. Springer, Singapore. 2020
Al-Shawi GS, Zena Kadhim Al-Younis KZ, Abd Al-Kareem FN. Study of cumin antibacterial and antioxidant activity of alcoholic and aqueous extract. Pakistan Journal of Biotechnology, 2017;14(2):227-231
Lianying F, Xiangxing W, Limin G and Qiang L. Antioxidant, Anti-microbial Properties and Chemical Composition of Cumin Essential Oils Extracted by Three Methods" Open Chemistry,2018; 6(1): 291-297.
Rani H., Sharma S., Bala, M. Technologies for extraction of oil from oilseeds and other plant sources in retrospect and prospects: A review. Journal of Food Process Engineering, 2021; 44 (11)
Sadiki FZ, Idrissi ME, Cioanca O, Trifan A, Hancianu M, Hritcu L, Postu PA. Tetraclinis articulata essential oil mitigates cognitive deficits and brain oxidative stress in an Alzheimer's disease amyloidosis model. Phytomedicine. 2019 Mar 15;56:57-63. doi: 10.1016/j.phymed.2018.10.032. Epub 2018 Oct 31. PMID: 30668354.
Derakhshan S, Navidinia M, Ahmadi A. (2017) Antibacterial Activity of Dill (Anethum graveolens) Essential Oil and Antibiofilm Activity of Cumin (Cuminum cyminum) Alcoholic Extract Infect Epidemiol Microbiol, 3(4): 122 -126
Kengne IC, Feugap LDT, Njouendou AJ, Ngnokam CDJ, Djamalladine MD, Ngnokam D, Voutquenne-Nazabadioko L, Tamokou JD. (2021) Antibacterial, antifungal and antioxidant activities of whole plant chemical constituents of Rumex abyssinicus. BMC Complement Med Ther., 5;21(1):164.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Medical and Pharmaceutical Sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
